SCHEMBL8722243

SCHEMBL8722243

CC(C)(C)N1CCC(C(O)C(=O)O)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 2/20 0.33
CPB2 Q96IY4 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948644 0.80 ATM (0.41) ATM
SCHEMBL8948794 0.79 CPN1 (0.33) CPN1CPB2ATM
SCHEMBL12423961 0.75 HTT (0.30)
SCHEMBL8948667 0.74 SMN1; SMN2 (0.50) CPN1CPB2
SCHEMBL26331973 0.74 ATM (0.33) CPN1CPB2ATM
SCHEMBL7141709 0.74 HPGD (0.51)
SCHEMBL20920353 0.74 ATM (0.31) ATM
SCHEMBL23673345 0.73
SCHEMBL10955186 0.73
SCHEMBL16815070 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885190-A1 NOVEL N-SUBSTITUTED 4-((4'-AMINOBENZOYL)-OXYMETHYL)-PIPERIDINES HAVING GASTRIC PROKINETIC PROPERTIES JANSSEN PHARMACEUTICA N.V. (BE) 1998-12-23 EP disclosed
WO-1997031897-A1 NOVEL N-SUBSTITUTED 4-((4'-AMINOBENZOYL)-OXYMETHYL)-PIPERIDINES HAVING GASTRIC PROKINETIC PROPERTIES JANSSEN PHARMACEUTICA N.V. (BE) 1997-09-04 WO disclosed
US-5532255-A Adhesion receptor antagonists MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-02 US disclosed