Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948684 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2HSD11B1CPN1CPB2 | |
| SCHEMBL8948737 | 0.80 | CYP3A4 (0.43) | SMN1; SMN2HSD11B1KDM4ECPN1CPB2 | |
| SCHEMBL28467709 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HSD11B1EPHX1KDM4ECPN1 | |
| SCHEMBL22048903 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HSD11B1KDM4ECPN1CPB2 | |
| SCHEMBL23673345 | 0.75 | — | — | |
| SCHEMBL10955186 | 0.75 | — | — | |
| SCHEMBL16815070 | 0.75 | — | — | |
| SCHEMBL8722243 | 0.74 | CPN1 (0.33) | CPN1CPB2 | |
| SCHEMBL8948610 | 0.74 | SIGMAR1 (0.55) | — | |
| SCHEMBL25147587 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD11B1EPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |