Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18813385 | 0.82 | LPAR3 (0.34) | LPAR3LPAR1LPAR2FDPSGGPS1 | |
| SCHEMBL6252620 | 0.80 | ALDH1A1 (0.36) | LPAR3LPAR1LPAR2FDPSALDH1A1 | |
| SCHEMBL8717738 | 0.80 | LPAR3 (0.33) | LPAR3LPAR1LPAR2FDPSGGPS1 | |
| SCHEMBL8717538 | 0.77 | LPAR3 (0.35) | LPAR3LPAR1LPAR2FDPSGGPS1 | |
| SCHEMBL8717140 | 0.75 | ALDH1A1 (0.45) | LPAR3LPAR1LPAR2ALDH1A1TSHR | |
| SCHEMBL8717529 | 0.75 | LPAR3 (0.38) | LPAR3LPAR1LPAR2FDPSGGPS1 | |
| SCHEMBL8962507 | 0.74 | FDPS (0.35) | FDPS | |
| SCHEMBL9126175 | 0.74 | FDPS (0.38) | LPAR3LPAR1LPAR2FDPSGGPS1 | |
| SCHEMBL8400655 | 0.74 | PPARD (0.38) | PPARDFDPSALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL8717546 | 0.74 | KDM4E (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854228-A | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-12-29 | — | — | US | disclosed |
| US-5650510-A | VIRICIDES OR ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-07-22 | — | — | US | disclosed |
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | disclosed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | disclosed |