Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463886 | 0.92 | PARP1 (0.46) | PARP1PARP2ALDH1A1KDM4ECNR1 | |
| SCHEMBL10426713 | 0.89 | KMT2A (0.43) | ALDH1A1KDM4ECNR1CNR2KMT2A | |
| SCHEMBL9760982 | 0.89 | PARP1 (0.44) | PARP1PARP2ALDH1A1KDM4ECNR1 | |
| SCHEMBL3373579 | 0.89 | PARP1 (0.50) | PARP1PARP2ALDH1A1KDM4ECNR1 | |
| SCHEMBL18040375 | 0.83 | PARP1 (0.57) | PARP1PARP2ALDH1A1KDM4ECNR1 | |
| SCHEMBL17387499 | 0.82 | KMT2A (0.47) | ALDH1A1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL10425887 | 0.82 | POLB (0.47) | ALDH1A1KDM4ECNR1CNR2KMT2A | |
| SCHEMBL8722305 | 0.80 | PARP1 (0.45) | PARP1PARP2ALDH1A1KDM4EKMT2A | |
| SCHEMBL377882 | 0.78 | SIGMAR1 (0.54) | PARP1PARP2ALDH1A1KDM4ECNR1 | |
| SCHEMBL18108811 | 0.76 | PARP1 (0.53) | PARP1PARP2ALDH1A1KDM4ECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005088-A1 | CATALYSTS WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE FOAM FORMULATIONS | ALLIED-SIGNAL INC. (US) | 1993-03-18 | — | — | WO | claimed |
| US-4937306-A | For polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-26 | — | — | US | claimed |
| EP-0300366-A1 | Non-fugitive aromatic diamine catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | claimed |
| US-5840779-A | COMPOSITION COMPRISING POLYISOCYANATE, POLYOL, HYDROFLUOROCARBON BLOWING AGENT, SURFACTANT, POLYAMINE CATALYST; DECREASED DECOMPOSITION OF BLOWING AGENT | ALLIEDSIGNAL INC. (US) | 1998-11-24 | — | — | US | disclosed |
| US-5688834-A | STABLE POLYURETHANE FOAMS | ALLIEDSIGNAL, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1993005088-A1 | CATALYSTS WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE FOAM FORMULATIONS | ALLIED-SIGNAL INC. (US) | 1993-03-18 | — | — | WO | disclosed |
| US-5034426-A | Reaction of polyisocyanate, polyol and a chain extender which is also a catalyst because of a tert-amine side chain | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4937306-A | For polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0300366-A1 | Non-fugitive aromatic diamine catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | disclosed |