Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316185 | 0.84 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL3451560 | 0.81 | TSHR (0.75) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL8722344 | 0.79 | TSHR (0.73) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL10333070 | 0.79 | TSHR (1.00) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL10333068 | 0.79 | TSHR (0.73) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL1283334 | 0.78 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL10394020 | 0.78 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL22789925 | 0.77 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL11894104 | 0.77 | POLB (0.77) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL3554810 | 0.77 | GPBAR1 (0.72) | ALDH1A1L3MBTL1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879237-A1 | ISOOXACEPHEM DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997026260-A1 | ISOOXACEPHEM DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-24 | — | — | WO | disclosed |