Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543471 | 0.77 | MAPK1 (0.51) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL14624200 | 0.75 | ADRA2C (0.59) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| Hydrochloric Acid SCHEMBL3474045 | 0.73 | ADRA2C (0.58) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL27506463 | 0.73 | ADRA2C (0.56) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL15690802 | 0.72 | ADRA2C (0.51) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL5543466 | 0.71 | MAPK1 (0.51) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL14355835 | 0.70 | TSHR (0.52) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL13159555 | 0.70 | MAPK1 (0.64) | NPBWR1MCHR1MAPK1POLBADRA2C | |
| SCHEMBL27762010 | 0.70 | ADRA2C (0.49) | MAPK1ADRA2CKMT2AMAPTEGFR | |
| SCHEMBL14355832 | 0.70 | HSD17B10 (0.71) | NPBWR1MCHR1MAPK1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |