Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | CASP7 | P55210 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355837 | 0.86 | MAPK1 (0.57) | HSD17B10MAPK1POLBCASP1CASP7 | |
| SCHEMBL18711850 | 0.84 | ALDH1A1 (0.70) | HSD17B10MAPK1POLBCASP1CASP7 | |
| SCHEMBL5558994 | 0.84 | POLB (0.66) | HSD17B10MAPK1POLBCASP1CASP7 | |
| SCHEMBL13159555 | 0.83 | MAPK1 (0.64) | HSD17B10MAPK1POLBCASP7GAA | |
| SCHEMBL19977050 | 0.82 | MAPK1 (0.63) | HSD17B10MAPK1POLBCASP1CASP7 | |
| SCHEMBL14355833 | 0.82 | GAA (0.80) | HSD17B10MAPK1POLBALDH1A1GAA | |
| SCHEMBL5337500 | 0.80 | ALDH1A1 (0.67) | HSD17B10MAPK1POLBCASP1CASP7 | |
| SCHEMBL14355836 | 0.79 | MAPK1 (0.60) | HSD17B10MAPK1POLBCASP7ALDH1A1 | |
| SCHEMBL14355804 | 0.77 | BRD9 (0.51) | HSD17B10MAPK1POLBCASP1CASP7 | |
| SCHEMBL8908801 | 0.77 | MAPK1 (0.57) | HSD17B10MAPK1POLBCASP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |