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SCHEMBL8722682

SCHEMBL8722682

COc1cc(N)c(Cl)cc1C(=O)N[C@H]1C[C@H]2CC[C@@H](C1)N2C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ HTR4 Q13639 7/20 1.00
▸ DRD2 P14416 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7292676 1.00 HTR4 (1.00) HTR4DRD2
SCHEMBL6949977 0.91 HTR4 (0.84) HTR4DRD2
SCHEMBL7292915 0.91 HTR4 (0.84) HTR4DRD2
SCHEMBL4897947 0.88 HTR4 (0.79) HTR4DRD2
SCHEMBL10413092 0.88 HTR4 (0.79) HTR4DRD2
Hydrochloric Acid SCHEMBL4887631 0.87 HTR4 (0.77) HTR4DRD2
SCHEMBL7299566 0.86 HTR4 (0.76) HTR4DRD2
SCHEMBL10412169 0.86 HTR4 (0.76) HTR4DRD2
SCHEMBL4887786 0.86 HTR4 (0.76) HTR4DRD2
SCHEMBL10523919 0.86 HTR4 (0.76) HTR4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712408-B1 TROPYL 7-AZAINDOL-3-YLCARBOXYAMIDES AS ANTITUSSIVE AGENT DOMPE SPA (IT) 1998-10-28 — — EP disclosed