Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720830 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL27492677 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL27490926 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL27511623 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL27510135 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7443090 | 0.75 | ITGB3 (1.00) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7350681 | 0.74 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL28741076 | 0.74 | ITGB3 (0.75) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7274636 | 0.74 | ITGB3 (0.98) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8720908 | 0.74 | ITGB3 (0.98) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879227-A1 | TYROSIN-DERIVATE AS ALPHA-V-INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997023451-A1 | TYROSIN-DERIVATE AS ALPHA-V-INTEGRIN INHIBITORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-07-03 | — | — | WO | disclosed |