Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722456 | 0.79 | RAD52 (0.37) | POLBSMN1; SMN2MAPTRAD52GFER | |
| SCHEMBL8722938 | 0.78 | AAK1 (0.40) | POLBMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8719317 | 0.78 | RAD52 (0.36) | POLBSMN1; SMN2MAPTRAD52GFER | |
| SCHEMBL8724171 | 0.74 | RAD52 (0.34) | POLBMAPTRAD52GFERALDH1A1 | |
| SCHEMBL22471168 | 0.66 | GFER (0.57) | SMN1; SMN2MAPTRAD52GFERKDM4E | |
| SCHEMBL8722985 | 0.65 | S1PR1 (0.43) | POLBMAPTTACR1KDM4EALDH1A1 | |
| SCHEMBL4581596 | 0.65 | SLC6A9 (0.39) | MAPTRAD52GFERALDH1A1 | |
| SCHEMBL8719295 | 0.65 | POLB (0.47) | POLBMAPTKDM4EALDH1A1CYP2C9 | |
| SCHEMBL8723002 | 0.65 | SLC6A9 (0.38) | MAPTRAD52GFERALDH1A1 | |
| SCHEMBL8722452 | 0.63 | MAPT (0.37) | POLBSMN1; SMN2MAPTRAD52GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814849-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO International B.V. (NL) | 1998-01-07 | — | — | EP | disclosed |