Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29813236 | 0.99 | CTSK (0.53) | CTSKSYKPSMB5CTSSCTSL | |
| SCHEMBL30999385 | 0.94 | CTSK (0.53) | CTSKSYKPSMB5CTSSCTSL | |
| SCHEMBL7904398 | 0.91 | CTSK (0.51) | CTSKSYKPSMB5CTSSCTSL | |
| SCHEMBL13570900 | 0.91 | SYK (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL9819558 | 0.91 | SYK (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL13570899 | 0.91 | SYK (0.55) | CTSKSYKCTSSCTSLCTSB | |
| SCHEMBL30999344 | 0.89 | PSMB5 (0.51) | CTSKSYKPSMB5CTSSCTSL | |
| SCHEMBL9819550 | 0.89 | CTSK (0.63) | CTSKPSMB5CTSSCTSLCTSB | |
| SCHEMBL19944560 | 0.88 | ECE1 (0.50) | CTSKSYKPSMB5CTSBREN | |
| SCHEMBL19325104 | 0.87 | SYK (0.51) | CTSKSYKPSMB5CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |