Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432815 | 0.89 | FABP4 (0.44) | ADRA1BMAPTFABP4FABP5MMP2 | |
| SCHEMBL11304673 | 0.83 | ADRA1B (0.48) | ADRA1BKDM4EAPEX1LMNAKMT2A | |
| SCHEMBL1571746 | 0.80 | ADRA1B (0.45) | ADRA1BMAPTMMP2MMP9ALDH1A1 | |
| SCHEMBL11428427 | 0.76 | ADRA1B (0.42) | ADRA1BLMNAMMP3MMP8TSHR | |
| SCHEMBL15461426 | 0.76 | ADRA1B (0.47) | ADRA1BMAPTMMP2MMP9KDM4E | |
| SCHEMBL11800493 | 0.75 | MEN1 (0.42) | ADRA1BMAPTFABP3FABP4FABP5 | |
| SCHEMBL14400476 | 0.75 | CYP2C19 (0.48) | ADRA1BMAPTMMP2MMP9KDM4E | |
| SCHEMBL11424253 | 0.73 | TDP1 (0.50) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15461431 | 0.72 | OPRL1 (0.41) | ADRA1BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11420415 | 0.71 | ADRA1B (0.44) | ADRA1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763191-A | BINDING MATRIX | BOEHRINGER MANNHEIM GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0515615-B1 | UNIVERSAL BINDING FILM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-04 | — | — | EP | disclosed |