Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549427 | 0.91 | ABCB1 (0.60) | ABCB1PTPN1ENPP2MAPTMEN1 | |
| SCHEMBL7909538 | 0.85 | ABCB1 (0.60) | ABCB1PTPN1ENPP2MAPTLMNA | |
| SCHEMBL7909609 | 0.81 | ABCB1 (0.56) | ABCB1PTPN1ENPP2MAPTLMNA | |
| SCHEMBL7909614 | 0.78 | ABCB1 (0.53) | ABCB1PTPN1ENPP2MAPTHTR1A | |
| SCHEMBL7914167 | 0.77 | ABCB1 (0.59) | ABCB1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30145233 | 0.77 | ABCB1 (0.59) | ABCB1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8723684 | 0.76 | ABCB1 (0.53) | ABCB1PTPN1ENPP2HTR1ADRD2 | |
| SCHEMBL8721199 | 0.75 | ABCB1 (0.49) | ABCB1PTPN1ENPP2ALDH1A1HTR1A | |
| SCHEMBL8241510 | 0.74 | ABCB1 (0.61) | ABCB1PTPN1ENPP2MAPTSMN1; SMN2 | |
| SCHEMBL10183792 | 0.74 | LIPE (0.66) | ABCB1PTPN1ENPP2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006691-A2 | LOW MOLECULAR WEIGHT DENDRITIC COMPOUNDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |