Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723181 | 0.80 | HIF1A (0.45) | POLQNR1H4GAAOPRL1HIF1A | |
| SCHEMBL8726648 | 0.79 | HIF1A (0.44) | POLQNR1H4GAAOPRL1HIF1A | |
| SCHEMBL8726645 | 0.79 | HIF1A (0.44) | POLQNR1H4GAAOPRL1HIF1A | |
| SCHEMBL8723182 | 0.78 | HIF1A (0.44) | POLQNR1H4GAAOPRL1HIF1A | |
| SCHEMBL8723178 | 0.78 | HIF1A (0.44) | POLQNR1H4GAAOPRL1HIF1A | |
| SCHEMBL31287376 | 0.78 | SYK (0.43) | ALDH1A1MAPTHPGDTDP1GAA | |
| SCHEMBL31287377 | 0.78 | SYK (0.43) | ALDH1A1MAPTHPGDTDP1GAA | |
| SCHEMBL7777172 | 0.78 | SYK (0.43) | ALDH1A1MAPTHPGDTDP1GAA | |
| SCHEMBL28334166 | 0.76 | HPGD (0.40) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL8723195 | 0.76 | ALDH1A1 (0.39) | POLQALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840726-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997001538-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1997-01-16 | — | — | WO | disclosed |