Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726648 | 0.93 | HIF1A (0.44) | HIF1AOPRL1POLQGAANR1H4 | |
| SCHEMBL8726645 | 0.93 | HIF1A (0.44) | HIF1AOPRL1POLQGAANR1H4 | |
| SCHEMBL8723178 | 0.92 | HIF1A (0.44) | HIF1AOPRL1POLQGAANR1H4 | |
| SCHEMBL8723182 | 0.92 | HIF1A (0.44) | HIF1AOPRL1POLQGAANR1H4 | |
| SCHEMBL9021163 | 0.84 | HIF1A (0.39) | HIF1AOPRL1 | |
| SCHEMBL5369743 | 0.80 | HIF1A (0.41) | HIF1AMRGPRX4 | |
| SCHEMBL7783632 | 0.80 | HIF1A (0.41) | HIF1AMRGPRX4 | |
| SCHEMBL10020202 | 0.80 | OPRL1 (0.38) | HIF1AOPRL1CYP3A4CD38 | |
| SCHEMBL8723192 | 0.80 | POLQ (0.46) | HIF1AOPRL1POLQGAANR1H4 | |
| SCHEMBL8171322 | 0.76 | MAPK1 (0.42) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840726-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997001538-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1997-01-16 | — | — | WO | disclosed |