Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | LIPE | Q05469 | 13/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718863 | 0.89 | CMA1 (0.37) | CMA1KCNH2MCHR1 | |
| SCHEMBL8105481 | 0.86 | HTT (0.39) | CMA1KCNH2MCHR1 | |
| SCHEMBL8723274 | 0.82 | USP2 (0.46) | CMA1 | |
| SCHEMBL8718847 | 0.80 | ACACB (0.41) | CMA1LIPEKCNH2MCHR1 | |
| SCHEMBL8721198 | 0.80 | POLB (0.49) | CMA1LIPESCN5AMCHR1 | |
| SCHEMBL5906085 | 0.79 | TRPV1 (0.41) | CMA1 | |
| SCHEMBL9016101 | 0.79 | CMA1 (0.35) | CMA1KCNH2MCHR1 | |
| SCHEMBL8111166 | 0.77 | TRPV1 (0.37) | CMA1KCNH2 | |
| SCHEMBL9232299 | 0.77 | HTT (0.54) | CMA1LIPESCN5A | |
| SCHEMBL16710172 | 0.76 | GPR3 (0.42) | LIPEKCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567982-B1 | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5466820-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0567982-A1 | Azole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |