Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | F7 | P08709 | 3/20 | 0.57 |
| ▸ | F3 | P13726 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723311 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL16503993 | 0.87 | ALDH1A1 (0.74) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL18179278 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL9283283 | 0.84 | ALDH1A1 (0.66) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL8720727 | 0.84 | FAAH (0.46) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL8720724 | 0.84 | FAAH (0.46) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL9283288 | 0.84 | ALDH1A1 (0.66) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL11847846 | 0.83 | FAAH (0.70) | CYP19A1PPARGF7F3KMT2A | |
| SCHEMBL28575816 | 0.83 | FAAH (0.65) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL11847839 | 0.83 | FAAH (0.70) | CYP19A1PPARGF7F3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783169-A | RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY | BROOKHAVEN SCIENCE ASSOCIATES LLC (US) | 1998-07-21 | — | — | US | claimed |
| JP-51138663-A | — | — | None | — | — | JP | disclosed |
| US-5783169-A | RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY | BROOKHAVEN SCIENCE ASSOCIATES LLC (US) | 1998-07-21 | — | — | US | disclosed |
| JP-S51138663-A | PROCESS FOR PREPARIN G ENDO-TRICYCLO )5.2.2.0 2.,6) UNDECA-8-EN-9-ONE | KAO CORP | 1976-11-30 | — | — | JP | disclosed |