Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.51 |
| ▸ | CDC25B | P30305 | 6/20 | 0.51 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.50 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.50 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943950 | 1.00 | HTR1A (0.52) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL21657199 | 1.00 | HTR1A (0.52) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL10408745 | 0.98 | HTR1A (0.53) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL10408744 | 0.98 | HTR1A (0.53) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL16229070 | 0.92 | PDE4D (0.50) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL13164466 | 0.92 | PDE4D (0.50) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL25031771 | 0.91 | GJB2 (0.53) | HTR1APDE4DNT5EPTPN1CDC25B | |
| SCHEMBL13608236 | 0.91 | PTPN1 (0.53) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL10408205 | 0.91 | PDE4D (0.51) | HTR1APDE4DNT5ESSTR1SSTR2 | |
| SCHEMBL10408203 | 0.91 | PDE4D (0.51) | HTR1APDE4DNT5ESSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832898-A2 | Substituted amino acid derivatives | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |