Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25369585 | 0.84 | KDM4E (0.46) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL30588898 | 0.84 | KDM4E (0.46) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL18029940 | 0.83 | KDM4E (0.46) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL6659911 | 0.78 | KDM4E (0.46) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL5996060 | 0.73 | HPGD (0.43) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL29590196 | 0.70 | KDM4E (0.62) | HPGDKDM4EGLAHSD17B10LMNA | |
| SCHEMBL7473565 | 0.69 | KDM4E (0.56) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL30830197 | 0.69 | KDM4E (0.56) | HPGDKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL5312088 | 0.69 | AKT1 (0.56) | HPGDLMNAPDE4D | |
| SCHEMBL31545199 | 0.69 | AKT1 (0.56) | HPGDLMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998034646-A2 | TARGETED ANTIOXIDANTS | UNIVERSITY OF HERTFORDSHIRE (GB) | 1998-08-13 | — | — | WO | disclosed |