Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907870 | 0.87 | DPP4 (0.37) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL8723458 | 0.78 | HPGD (0.49) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL30588898 | 0.75 | KDM4E (0.46) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL25369585 | 0.75 | KDM4E (0.46) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL23246626 | 0.70 | KDM4E (0.58) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL9113086 | 0.69 | SIGMAR1 (0.46) | TSHR | |
| SCHEMBL7473565 | 0.67 | KDM4E (0.56) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL30830197 | 0.67 | KDM4E (0.56) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL18029940 | 0.67 | KDM4E (0.46) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 | |
| Water SCHEMBL16634424 | 0.66 | KDM4E (0.54) | KDM4EHPGDHSD17B10CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060223-B1 | PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME | INST NEUE MAT GEMEIN GMBH (DE) | 2004-08-18 | — | — | EP | disclosed |
| EP-1060223-A1 | PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME | Institut Für Neue Materialien gem. GmbH (DE) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999041326-A1 | PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME | INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) | 1999-08-19 | — | — | WO | disclosed |