SCHEMBL7473565

SCHEMBL7473565

c1ccc2c3c(ccc2c1)OCC3

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
HSD17B10 Q99714 2/20 0.56
CYP1A2 P05177 2/20 0.56
GLA P06280 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C19 P33261 1/20 0.56
SIRT1 Q96EB6 1/20 0.56
MAPT P10636 1/20 0.53
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
VDR P11473 1/20 0.42
ITGB2 P05107 1/20 0.39
ICAM1 P05362 1/20 0.39
ITGAL P20701 1/20 0.39
HPRT1 P00492 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30830197 1.00 KDM4E (0.56) KDM4EHSD17B10CYP1A2GLACYP2C9
Water SCHEMBL16634424 0.98 KDM4E (0.54) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL29269339 0.91 HPRT1 (0.50) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL29670013 0.89 KDM4E (0.53) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL30003445 0.89 KDM4E (0.53) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL371993 0.89 KDM4E (0.53) KDM4EHSD17B10CYP1A2GLACYP2C9
Acetic Acid SCHEMBL11711913 0.88 KDM4E (0.50) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL14158873 0.85 KDM4E (0.41) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL1123737 0.81 KDM4E (0.53) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL372146 0.80 HPRT1 (0.47) KDM4EHSD17B10CYP1A2GLACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2026-02-19 US disclosed
WO-2025051340-A1 TRPM8 MODULATORS AND RELATED METHOD FOR MODULATING TRPM8 RECEPTORS SYMRISE AG (DE) 2025-03-13 WO disclosed
US-20230212483-A1 Improvements in or Relating to Organic Compounds GIVAUDAN SA (CH) 2023-07-06 US disclosed
CN-113861169-A Polysubstituted naphtho-dihydrofuran compound, preparation method and application thereof 西华大学 2021-12-31 CN disclosed
US-10806683-B2 Encapsulated perfume compositions GIVAUDAN SA (CH) 2020-10-20 US disclosed
US-10722857-B2 Encapsulated perfume compositions GIVAUDAN S.A. (CH) 2020-07-28 US disclosed
US-10537868-B2 Microcapsules GIVAUDAN S.A. (CH) 2020-01-21 US disclosed
US-20180185808-A1 MICROCAPSULES GIVAUDAN SA (CH) 2018-07-05 US disclosed
US-20180177689-A1 IMPROVEMENTS IN OR RELATING TO ENCAPSULATED PERFUME COMPOSITIONS GIVAUDAN S.A. (CH) 2018-06-28 US disclosed
US-20180169603-A1 IMPROVEMENTS IN OR RELATING TO ENCAPSULATED PERFUME COMPOSITIONS GIVAUDAN S.A. (CH) 2018-06-21 US disclosed
US-20140357682-A1 ANDROGEN RECEPTOR LIGANDS The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of The College of the Holy (IE) 2014-12-04 US disclosed
WO-2013076275-A1 ANDROGEN RECEPTOR LIGANDS THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIV.TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2013-05-30 WO disclosed
US-8034949-B2 Pyrrolidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-10-11 US disclosed
US-8034949-B2 Pyrrolidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-10-11 US disclosed
US-20070167440-A1 Novel pyrrolidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-07-19 US disclosed
US-20070167440-A1 Novel pyrrolidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-07-19 US disclosed
EP-1222174-A1 IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE Takeda Chemical Industries, Ltd. (JP) 2002-07-17 EP disclosed
WO-2001030762-A1 IMIDAZOL-4-YLMETHANOLS USE AS INHIBITORS OF STEROID C17-20 LYASE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-03 WO disclosed
CN-1103866-A Nes pesticides RHONE POULENC AGRICULTURE (GB) 1995-06-21 CN disclosed
EP-0023080-B1 SUBSTITUTED 2,7-DIOXO-2,7-DIHYDROBENZO(1:2-B; 5,6-B1)DIFURAN OR DIPYRROLE DYESTUFFS, PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR THE COLOURATION OF AROMATIC POLYESTER TEXTILE MATERIALS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167440-A1 Novel pyrrolidine compound and a process for preparing the same CNR1, CNR2, OPRD1 KDM4E 535/4885HSD17B10 1741/4885CYP1A2 580/4885
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL RBP4, LRAT, RARB KDM4E 1000/4885HSD17B10 61/4885CYP1A2 3874/4885
US-20140357682-A1 ANDROGEN RECEPTOR LIGANDS AR, NR5A1, SHBG KDM4E 3767/4885HSD17B10 333/4885CYP1A2 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.