Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789940 | 0.84 | TSHR (0.65) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9042119 | 0.83 | TSHR (0.62) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL739464 | 0.82 | TSHR (0.71) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL28362327 | 0.81 | TSHR (0.59) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL11382549 | 0.78 | TSHR (0.65) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL27714530 | 0.78 | TSHR (0.65) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6061476 | 0.76 | TSHR (0.56) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6061675 | 0.76 | TSHR (0.56) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6061301 | 0.76 | TSHR (0.56) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL451074 | 0.76 | ALDH1A1 (0.68) | TSHRALDH1A1HSD17B10KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800624-A | LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER | UNIVERSITY OF NOTRE DAME (US) | 1998-09-01 | — | — | US | disclosed |