SCHEMBL451074

SCHEMBL451074

CCCCCCCCCCCCOC(=O)c1ccccc1C(C)CCCCCC

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
TSHR P16473 4/20 0.68
LMNA P02545 2/20 0.68
CYP3A4 P08684 2/20 0.66
MAPK1 P28482 2/20 0.66
TP53 P04637 1/20 0.66
HSD17B10 Q99714 2/20 0.60
KDM4E B2RXH2 2/20 0.60
POLB P06746 1/20 0.60
L3MBTL1 Q9Y468 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3220484 0.89 ALDH1A1 (0.77) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL29139944 0.85 ALDH1A1 (0.50) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL11412855 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL2966531 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL7807326 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL7807334 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL1681461 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL2973660 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL9359589 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL7797240 0.85 ALDH1A1 (0.79) ALDH1A1TSHRLMNACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118338884-A Oxidizing agent and acid based systems and therapies for enhancing skin appearance 欧莱雅 2024-07-12 CN disclosed
WO-2024141749-A1 GLOSSY NON-TRANSFER COMPOSITION L V M H RECHERCHE (FR) 2024-07-04 WO disclosed
WO-2024110067-A1 OIL-IN-WATER EMULSION COMPRISING AN EMULSIFIER SYSTEM CONSISTING OF A CYCLODEXTRIN AND AN EMULSIFIER OF STARCH ORIGIN ROQUETTE FRERES (FR) 2024-05-30 WO disclosed
WO-2024018159-A1 ANHYDROUS MAKE-UP COMPOSITION L V M H RECHERCHE (FR) 2024-01-25 WO disclosed
EP-4127050-A1 EMULSIFYING AND TEXTURING COMPOSITION BASED ON STARCHES AND GUMS, FOR COSMETICS ROQUETTE FRERES (FR) 2023-02-08 EP disclosed
CN-112312879-A Emulsions comprising silicone resin, liquid polyol, and pigment, preparation of emulsions, and methods of use thereof 莱雅公司 2021-02-02 CN disclosed
CN-111163747-A Matte lipstick composition 香奈儿香水美妆品公司 2020-05-15 CN disclosed
CN-105392530-A Oil/oil emulsions containing particles with a breakage of curvature, compositions comprising them and use of the particles for stabilizing o/o emulsions OREAL 2016-03-09 CN disclosed
US-20120064019-A1 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD L'OREAL (FR) 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120064019-A1 COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD PLOD3, ALOX15, ELOVL1 ALDH1A1 3221/4885TSHR 2894/4885LMNA 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.