SCHEMBL8723669

SCHEMBL8723669

CC1CCCCN1NC(O)=S

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
GAA P10253 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MGLL Q99685 1/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.31
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28394458 0.94 HTT (0.36) HTTGAANPC1RAB9ANPSR1
N-Methylpiperidine SCHEMBL28912564 0.87 HTT (0.33) HTTGAANPC1RAB9ANPSR1
SCHEMBL6336369 0.74 ALDH1A1 (0.41) GAAKMT2APOLBHPGDALDH1A1
SCHEMBL7515932 0.72 KMT2A (0.53) GAANPC1RAB9ANPSR1KMT2A
SCHEMBL9222113 0.72
SCHEMBL23581940 0.71 HPGD (0.37) GAAKMT2AHPGDALDH1A1MAPT
SCHEMBL5350659 0.71 AKR1C3 (0.38) GAAKMT2APOLBHPGDALDH1A1
SCHEMBL5350664 0.71 AKR1C3 (0.38) GAAKMT2APOLBHPGDALDH1A1
SCHEMBL11681085 0.71 SMN1; SMN2 (0.40) GAAKMT2APOLBL3MBTL1HPGD
SCHEMBL5350661 0.71 AKR1C3 (0.38) GAAKMT2APOLBHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed