SCHEMBL7515932

SCHEMBL7515932

CCCCNC(=S)NN1CCCCC1C

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
FKBP1A P62942 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
LMNA P02545 1/20 0.35
NAAA Q02083 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7509993 0.74 ALDH1A1 (0.55) KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL7512448 0.72 KMT2A (0.48) KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL8723669 0.72 HTT (0.39) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL27910552 0.69 KMT2A (1.00) KMT2AMEN1ALDH1A1LMNA
SCHEMBL1306068 0.69 CXCR4 (0.34) KMT2AMEN1ALDH1A1KDM4EGAA
SCHEMBL28394458 0.68 HTT (0.36) KMT2AALDH1A1GAAMAPTNPSR1
SCHEMBL13684848 0.68 KMT2A (0.96) KMT2AMEN1ALDH1A1LMNA
SCHEMBL7512945 0.68 KMT2A (0.45) KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL17219 0.67 KMT2A (0.57) KMT2AMEN1ALDH1A1SMN1; SMN2GAA
SCHEMBL7507205 0.66 LMNA (0.53) KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0876300-B1 USE OF THIOUREA COMPOUNDS FOR CONTROLLING BIOFOULING BUCKMAN LABOR INC (US) 2002-01-02 EP claimed
US-6075022-A Methods and compositions for controlling biofouling using thiourea compounds BUCKMAN LABORATORIES INTERNATIONAL INC. (US) 2000-06-13 US claimed
EP-0876300-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1998-11-11 EP claimed
WO-1997011911-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1997-04-03 WO claimed
EP-0876300-B1 USE OF THIOUREA COMPOUNDS FOR CONTROLLING BIOFOULING BUCKMAN LABOR INC (US) 2002-01-02 EP disclosed
US-6075022-A Methods and compositions for controlling biofouling using thiourea compounds BUCKMAN LABORATORIES INTERNATIONAL INC. (US) 2000-06-13 US disclosed
EP-0876300-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1998-11-11 EP disclosed
WO-1997011911-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1997-04-03 WO disclosed