Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728887 | 0.90 | HSD17B10 (0.40) | HSD17B10CES2 | |
| SCHEMBL8725930 | 0.86 | CES2 (0.45) | CES2 | |
| SCHEMBL8728580 | 0.80 | — | — | |
| SCHEMBL14302813 | 0.80 | — | — | |
| SCHEMBL1058224 | 0.79 | — | — | |
| SCHEMBL27243680 | 0.75 | TSHR (0.50) | CES2 | |
| SCHEMBL13258711 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL20057325 | 0.74 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL11415281 | 0.73 | CES2 (0.56) | CES2 | |
| SCHEMBL294859 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |