Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727226 | 0.91 | F2 (0.34) | F2PRSS1TMPRSS15F10 | |
| SCHEMBL8933084 | 0.85 | F2 (0.33) | F2F10 | |
| SCHEMBL6477416 | 0.85 | F2 (0.39) | F2PRSS1F10ITGB3ITGA2B | |
| SCHEMBL6483869 | 0.82 | F2 (0.35) | F2PRSS1F10ITGB3ITGA2B | |
| SCHEMBL6477095 | 0.80 | F2 (0.38) | F2F10ITGB3ITGA2B | |
| SCHEMBL8933063 | 0.77 | P2RX7 (0.34) | F2 | |
| SCHEMBL8721666 | 0.77 | F2 (0.35) | F2PRSS1F10 | |
| SCHEMBL6484699 | 0.76 | PROC (0.42) | F2PRSS1TMPRSS15F10ITGB3 | |
| SCHEMBL8781109 | 0.74 | F2 (0.36) | F2PRSS1F10 | |
| SCHEMBL8725900 | 0.74 | F2 (0.31) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |