Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722625 | 0.85 | TLR7 (0.62) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL8725704 | 0.82 | TLR7 (0.46) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL8727254 | 0.82 | TLR7 (0.43) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL2706297 | 0.82 | TLR7 (0.58) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL3183969 | 0.80 | TLR7 (0.62) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL2706302 | 0.79 | TLR7 (0.58) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL24499504 | 0.79 | PI4KA (0.39) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL4753594 | 0.78 | TLR7 (0.59) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL22761521 | 0.78 | TLR7 (0.60) | TLR7ADORA2ANUDT1LMNAPOLB | |
| SCHEMBL22761522 | 0.78 | TLR7 (0.60) | TLR7ADORA2ANUDT1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756747-A | 1H-imidazo 4,5-c!quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0385630-B1 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES INC (US) | 1996-11-27 | — | — | EP | disclosed |
| EP-0389302-B1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES INC (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5037986-A | Olefinic 1H-imidazo[4,5-c]quinolin-4-amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0389302-A1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0385630-A2 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES, INC. (US) | 1990-09-05 | — | — | EP | disclosed |