SCHEMBL24499504

SCHEMBL24499504

CC(C)(C)n1cnc2c3ccccc3c3ccccc3c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39
PI4K2A Q9BTU6 1/20 0.39
PI4KB Q9UBF8 1/20 0.39
LMNA P02545 3/20 0.38
MAPT P10636 3/20 0.38
TLR7 Q9NYK1 2/20 0.38
PDE4D Q08499 4/20 0.33
POLB P06746 1/20 0.33
HRH2 P25021 1/20 0.33
ADRA1D P25100 1/20 0.33
HTR2A P28223 1/20 0.33
ADORA2A P29274 1/20 0.33
ADRA1A P35348 1/20 0.33
NUDT1 P36639 1/20 0.33
HTR2B P41595 1/20 0.33
KCNH2 Q12809 1/20 0.33
PDE4A P27815 3/20 0.33
PDE4B Q07343 3/20 0.33
PDE4C Q08493 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723784 0.79 TLR7 (0.62) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL8725704 0.76 TLR7 (0.46) LMNATLR7PDE4DPOLBHRH2
SCHEMBL20127221 0.75 PDE4D (0.48) LMNAMAPTTLR7PDE4DPOLB
SCHEMBL6098811 0.72 KDM4E (0.38) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL9195572 0.70 SMN1; SMN2 (0.51) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL8721713 0.70 KDM4E (0.39) MAPTTLR7POLBHPGDNPC1
SCHEMBL15907143 0.69 PI4KA (0.41) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL15906393 0.68 FGFR1 (0.46) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL122153 0.66 POLB (0.51) POLBHPGDNPC1RAB9AKDM4E
SCHEMBL8721699 0.65 HPGD (0.34) LMNAMAPTTLR7HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230101042-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES U.S. DEPARTMENT OF ENERGY 2023-03-30 US disclosed
US-20220185826-A1 Tandem Carbene Phosphors THE UNIVERSITY OF SOUTHERN CALIFORNIA 2022-06-16 US disclosed
US-20220181562-A1 Tandem-Carbene Phosphors THE UNIVERSITY OF SOUTHERN CALIFORNIA 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185826-A1 Tandem Carbene Phosphors OCIAD1, CCND2, OCIAD2 PI4KA 786/4885PI4K2B 552/4885PI4K2A 679/4885
US-20220181562-A1 Tandem-Carbene Phosphors OCIAD2, OCIAD1, DUOX2 PI4KA 1520/4885PI4K2B 1046/4885PI4K2A 843/4885
US-20230101042-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, AOC2 PI4KA 2969/4885PI4K2B 2706/4885PI4K2A 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.