Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 12/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxybenzone SCHEMBL8723921 | 1.00 | LMNA (0.53) | LMNAMAPK1HPGDCYP2C19ALDH1A1 | |
| Phenol SCHEMBL8729267 | 0.87 | TDP1 (0.54) | LMNAALDH1A1TDP1MAPTRECQL | |
| Octinoxate SCHEMBL4163967 | 0.84 | TDP1 (0.72) | LMNAMAPK1HPGDCYP2C19ALDH1A1 | |
| 4-Methoxycinnamic Acid SCHEMBL21195188 | 0.84 | TDP1 (0.55) | LMNAALDH1A1TDP1MAPTRECQL | |
| SCHEMBL14698300 | 0.84 | TDP1 (0.62) | LMNATDP1MAPTATMMEN1 | |
| SCHEMBL35994 | 0.84 | TDP1 (0.62) | LMNATDP1MAPTATMMEN1 | |
| SCHEMBL35995 | 0.84 | TDP1 (0.62) | LMNATDP1MAPTATMMEN1 | |
| 4-Methoxycinnamic Acid SCHEMBL19717781 | 0.83 | TDP1 (0.58) | LMNATDP1MAPTNPC1RECQL | |
| SCHEMBL28036638 | 0.83 | TDP1 (0.61) | LMNATDP1MAPTATMMEN1 | |
| SCHEMBL670602 | 0.83 | MAOB (0.52) | LMNAMAPK1HPGDCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827506-A | MIXTURE OF DIHYDROXYACETONE AND AN AMINO ACID FOR APPLICATION TO SKIN | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0501714-B1 | Cationic compositions for skin | UNILEVER PLC (GB) | 1997-05-02 | — | — | EP | disclosed |