Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.77 |
| ▸ | CES1 | P23141 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544074 | 0.87 | CES2 (1.00) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL6317444 | 0.87 | CES2 (1.00) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL2156567 | 0.87 | CES2 (1.00) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL31138026 | 0.83 | CES2 (0.81) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL15180840 | 0.81 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL1509797 | 0.81 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL31633743 | 0.81 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL93276 | 0.80 | CES2 (0.68) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL28272323 | 0.80 | CES2 (0.68) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL29368196 | 0.80 | CES2 (0.68) | CES2CES1ALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849783-A | Autobiotics and their use in eliminating nonself cells | CELL RESEARCH CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0537267-B1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO | CELL RES CORP (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0537267-A1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO. | CELL RES CORP (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5147652-A | Alpha ketoaldehydes | CELL RESEARCH CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| WO-1992000727-A1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO | CELL RESEARCH CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |