SCHEMBL8723959

SCHEMBL8723959

Cc1ccc2cccc(OCc3c(Cl)ccc(C(=O)N4CCNCC4)c3Cl)c2n1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7661562 0.99 BDKRB2 (0.66) BDKRB2
SCHEMBL7660533 0.86 BDKRB2 (0.56) BDKRB2
SCHEMBL7665419 0.85 BDKRB2 (0.57) BDKRB2
SCHEMBL7010477 0.82 BDKRB2 (0.61) BDKRB2
SCHEMBL7665934 0.81 BDKRB2 (0.55) BDKRB2
SCHEMBL7662929 0.81 BDKRB2 (0.64) BDKRB2
SCHEMBL7662932 0.81 BDKRB2 (0.64) BDKRB2
SCHEMBL4056235 0.80 BDKRB2 (1.00) BDKRB2
SCHEMBL7805291 0.79 BDKRB2 (0.67) BDKRB2
SCHEMBL7805295 0.79 BDKRB2 (0.67) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0861243-A1 HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-09-02 EP disclosed
WO-1997011069-A1 HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-27 WO disclosed