Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383236 | 0.85 | HTR1A (0.52) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| SCHEMBL30908963 | 0.85 | HTR1A (0.52) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| Potassium Ion SCHEMBL8711597 | 0.83 | HTR1A (0.50) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| SCHEMBL6194848 | 0.80 | HTR1A (0.56) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| SCHEMBL2781828 | 0.75 | HTR1A (0.53) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| Hydrochloric Acid SCHEMBL2779321 | 0.75 | HTR1A (0.53) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| SCHEMBL30908976 | 0.73 | NOS3 (0.42) | LMNAPOLBMAPTTP53 | |
| SCHEMBL8721916 | 0.73 | NOS3 (0.47) | HTR1AKDM4ESLC6A4HSD17B10POLB | |
| Hydrochloric Acid SCHEMBL11439099 | 0.72 | SLC6A4 (1.00) | HTR1AKDM4EALOX15LMNASLC6A4 | |
| SCHEMBL4674658 | 0.72 | SLC6A4 (1.00) | HTR1AKDM4EALOX15LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |