SCHEMBL872409

SCHEMBL872409

CCCNc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 4/20 0.57
ALDH1A1 P00352 2/20 0.50
POLB P06746 1/20 0.50
HDAC3 O15379 3/20 0.49
HDAC1 Q13547 3/20 0.49
HDAC2 Q92769 3/20 0.49
NCOR2 Q9Y618 2/20 0.49
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
MITF O75030 1/20 0.46
FYN P06241 1/20 0.46
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RARB P10826 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL417750 0.89 HCAR3 (0.59) HCAR3TP53TSHRRARBLMNA
SCHEMBL2825925 0.87 HCAR3 (0.60) HCAR3TP53TSHRRARBLMNA
Paraben SCHEMBL5310599 0.86 CA12 (0.52) HCAR3ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL82488 0.86 ALDH1A1 (0.49) HCAR3ALDH1A1POLBHDAC3HDAC1
Cetaben SCHEMBL2112078 0.85 HCAR3 (0.59) HCAR3ALDH1A1TP53TSHRRARB
SCHEMBL11280086 0.85 HCAR3 (0.59) HCAR3ALDH1A1TP53TSHRRARB
SCHEMBL2309354 0.85 HCAR3 (0.59) HCAR3ALDH1A1TP53TSHRRARB
SCHEMBL22398313 0.85 HCAR3 (0.59) HCAR3ALDH1A1TP53TSHRRARB
SCHEMBL10534588 0.85 HCAR3 (0.59) HCAR3ALDH1A1TP53TSHRRARB
SCHEMBL6372020 0.85 HCAR3 (0.59) HCAR3ALDH1A1TP53TSHRRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112010856-B Folic acid telescoping process method by utilizing microchannel reaction 威海中腾医药科技有限公司 2023-05-16 CN claimed
CN-116103349-A Enzyme-catalyzed folic acid green synthesis method 苏州伯凯医药科技有限公司 2023-05-12 CN claimed
CN-112010856-A Telescoping process method for preparing folic acid by using microchannel reaction 威海中腾医药科技有限公司 2020-12-01 CN claimed
CN-110105362-B Safe and green folic acid synthesis method catalyzed by heteropoly acid 威海中腾医药科技有限公司 2020-10-23 CN claimed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US claimed
US-20060110743-A1 Drug evolution: drug design at hot spots KONISHI YASUO 2006-05-25 US claimed
WO-2002095393-A2 DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2002-11-28 WO claimed
JP-62280072-A None JP disclosed
EP-4559903-A1 PRODUCTION METHOD FOR TAFAMIDIS OR SALT THEREOF Shiratori Pharmaceutical Co., Ltd. (JP) 2025-05-28 EP disclosed
WO-2025086591-A1 ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 烟台药物研究所 2025-05-01 WO disclosed
CN-119585243-A Process for producing cloxazoic acid or salt thereof 白鸟制药株式会社 2025-03-07 CN disclosed
CN-117105906-B Rotigotine prodrug derivatives, pharmaceutical compositions and uses thereof 烟台药物研究所 2024-01-30 CN disclosed
WO-2024019180-A1 PRODUCTION METHOD FOR TAFAMIDIS OR SALT THEREOF 白鳥製薬株式会社 2024-01-25 WO disclosed
US-5043315-A Aromatic or heterocyclic isocyanate and imino compound MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US disclosed
US-5043312-A Mixture of imino and isocyanate compounds, biphenyl alcohol in binder on support; image preservation, heat responsiveness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US disclosed
EP-0439638-A1 Heat sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-08-07 EP disclosed
US-5036039-A Aromatic isocyanate and imine MITSUBISHI PAPER MILLS LIMITED (JP) 1991-07-30 US disclosed
EP-0427929-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-05-22 EP disclosed
US-4965237-A AROMATICITY-POSESSING ISOCYANATE COMPOUND, IMINO COMPOUND, AND ANILINE DERIVATIVE MITSUBISHI PAPER MILLS, LTD. (JP) 1990-10-23 US disclosed
JP-S62280072-A THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1987-12-04 JP disclosed