SCHEMBL8724248

SCHEMBL8724248

NOP(=O)(Cl)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 1/20 0.44
HTT P42858 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ANPEP P15144 2/20 0.40
LAP3 P28838 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122230 0.86 SRC (0.58) SRCL3MBTL1TDP1KDM4EHTT
Water SCHEMBL7889250 0.84 SRC (0.56) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL5270418 0.80 SRC (0.52) SRCL3MBTL1TDP1KDM4EHTT
Methylene Chloride SCHEMBL29220060 0.80 SRC (0.52) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL11433980 0.78 SRC (0.50) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL2851613 0.77 SRC (0.54) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL2851714 0.77 SRC (0.54) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL13894009 0.77 L3MBTL1 (0.58) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL31249523 0.77 L3MBTL1 (0.57) SRCL3MBTL1TDP1KDM4EHTT
SCHEMBL259733 0.77 SRC (0.58) SRCL3MBTL1TDP1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998008875-A1 NOVEL COMBINATION PREPARATIONS AND THEIR USE IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY VIVA DIAGNOSTIKA DIAGNOSTISCHE PRODUKTE GMBH (DE) 1998-03-05 WO claimed
WO-1998008875-A1 NOVEL COMBINATION PREPARATIONS AND THEIR USE IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY VIVA DIAGNOSTIKA DIAGNOSTISCHE PRODUKTE GMBH (DE) 1998-03-05 WO disclosed