Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.50 |
| ▸ | EP300 | Q09472 | 3/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583416 | 0.93 | BID (0.52) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8518967 | 0.93 | BID (0.52) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL84570 | 0.92 | BID (0.50) | BIDMCL1BCL2L1BAK1KAT8 | |
| Hydrogen Sulfide SCHEMBL5261196 | 0.90 | BID (0.49) | BIDMCL1BCL2L1BAK1KAT8 | |
| Phosphoric Acid SCHEMBL28511309 | 0.88 | BID (0.48) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL11814659 | 0.87 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| Isopropylamine SCHEMBL28049903 | 0.87 | BID (0.47) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28352834 | 0.84 | THRA (0.43) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28677888 | 0.84 | THRA (0.43) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28356583 | 0.84 | THRA (0.43) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705467-A | ALKYL ETHER SULFATE, TERPENE DERIVATIVE, ALKYLPHENOL SULFATE SALT, ALKALI METAL HYPOCHLORITE, AND SOLVENT; HARD SURFACES | CHOY CLEMENT K (US) | 1998-01-06 | — | — | US | claimed |