SCHEMBL8724554

SCHEMBL8724554

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccccc2NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.81
LMNA P02545 4/20 0.74
KMT2A Q03164 2/20 0.68
ALDH1A1 P00352 3/20 0.67
TSHR P16473 2/20 0.67
SMN1; SMN2 Q16637 1/20 0.63
TP53 P04637 1/20 0.61
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA4 P22748 1/20 0.61
CA6 P23280 1/20 0.61
CA5A P35218 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA13 Q8N1Q1 1/20 0.61
CA14 Q9ULX7 1/20 0.61
NLRP3 Q96P20 3/20 0.61
KDM4E B2RXH2 2/20 0.61
GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567802 0.94 LMNA (0.74) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL5185904 0.92 L3MBTL1 (0.74) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL21987760 0.91 LMNA (0.70) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL20568982 0.91 LMNA (0.70) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL31441305 0.91 L3MBTL1 (0.72) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL6464247 0.90 L3MBTL1 (0.72) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL5184786 0.90 L3MBTL1 (0.71) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL6243122 0.89 L3MBTL1 (0.70) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL8418021 0.89 L3MBTL1 (0.70) L3MBTL1LMNAKMT2AALDH1A1TSHR
SCHEMBL6436108 0.88 L3MBTL1 (0.69) L3MBTL1LMNAKMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10044619-A None JP disclosed
JP-H1044619-A NEW DEVELOPER COMPOSED OF BIS(P-TOLUENESULFONYLAMINO CARBONYLAMINO)-BENZENE DERIVATIVE KEMIPURO KASEI KK 1998-02-17 JP disclosed