⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872465 | 0.81 | GAA (0.32) | — | |
| SCHEMBL1964653 | 0.80 | GAA (0.33) | — | |
| SCHEMBL12285214 | 0.79 | — | — | |
| SCHEMBL1922449 | 0.79 | — | — | |
| SCHEMBL8813250 | 0.79 | — | — | |
| SCHEMBL8811138 | 0.77 | — | — | |
| SCHEMBL18657151 | 0.77 | — | — | |
| SCHEMBL8811134 | 0.77 | — | — | |
| SCHEMBL11844262 | 0.77 | — | — | |
| SCHEMBL4847688 | 0.77 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10155007-B2 | Synthesis method for improved tenofovir disoproxil fumarate using ion-exchange resin and method for preparing oral dissolving film form using the same | FIRSON (KR) | 2018-12-18 | — | — | US | claimed |
| CN-104974188-A | Tenofovir disoproxil crystal form and preparation method thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2015-10-14 | — | — | CN | claimed |
| EP-4371979-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023207942-A1 | NUCLEOSIDE DRUG FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | 北京沐华生物科技有限责任公司 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023286855-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | クミアイ化学工業株式会社 | 2023-01-19 | — | — | WO | disclosed |
| CN-107148423-B | Thionucleoside derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2021-07-30 | — | — | CN | disclosed |
| EP-3145936-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3150608-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-04-10 | — | — | EP | disclosed |
| CN-104974188-B | A kind of tenofovir disoproxil crystal form and preparation method thereof | 浙江九洲药业股份有限公司 | 2019-01-08 | — | — | CN | disclosed |
| US-9963467-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| CN-107973833-A | Design as the oligonucleotide analogs of therapeutic agent | 斯普林银行医药公司 | 2018-05-01 | — | — | CN | disclosed |
| US-5922695-A | COMPOUNDS CONTAINING CARBONATE OR CARBAMATE GROUPS | GILEAD SCIENCES, INC. (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0915894-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1999005150-A1 | NUCLEOTIDE ANALOG COMPOSITION AND SYNTHESIS METHOD | GILEAD SCIENCES, INC. (US) | 1999-02-04 | — | — | WO | disclosed |
| WO-1998004569-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1998-02-05 | — | — | WO | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| WO-1997030036-A1 | ARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-08-21 | — | — | WO | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| CN-85105429-A | The preparation desugar is the method for the carboxylates derivatives of Aaron Copland peaceful (deglucoteicoplanin) too | — | 1987-01-14 | — | — | CN | disclosed |