Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922449 | 0.81 | — | — | |
| SCHEMBL8813250 | 0.81 | — | — | |
| SCHEMBL12285214 | 0.81 | — | — | |
| SCHEMBL872466 | 0.81 | — | — | |
| SCHEMBL18657151 | 0.79 | — | — | |
| SCHEMBL8811138 | 0.79 | — | — | |
| SCHEMBL8811134 | 0.79 | — | — | |
| SCHEMBL28079757 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL17580217 | 0.75 | KDM4E (0.30) | — | |
| SCHEMBL475144 | 0.74 | TSHR (0.43) | GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10155007-B2 | Synthesis method for improved tenofovir disoproxil fumarate using ion-exchange resin and method for preparing oral dissolving film form using the same | FIRSON (KR) | 2018-12-18 | — | — | US | claimed |
| WO-2023207942-A1 | NUCLEOSIDE DRUG FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | 北京沐华生物科技有限责任公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-107148423-B | Thionucleoside derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2021-07-30 | — | — | CN | disclosed |
| EP-3145936-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3150608-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-04-10 | — | — | EP | disclosed |
| CN-104974188-B | A kind of tenofovir disoproxil crystal form and preparation method thereof | 浙江九洲药业股份有限公司 | 2019-01-08 | — | — | CN | disclosed |
| US-9963467-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| EP-3150608-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20170088561-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA, INC. | 2017-03-30 | — | — | US | disclosed |
| EP-3145936-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2017-03-29 | — | — | EP | disclosed |
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-7973013-B2 | 2'-fluoro substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| CN-102093417-A | Compound capable of being used for preparing nucleoside phosphoric acid medicaments and preparation method thereof | JINAN INOVAS CHEMICAL CO LTD | 2011-06-15 | — | — | CN | disclosed |
| US-20110070194-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| CN-101574356-A | Tenofovir disoproxil pharmaceutical salt and preparations thereof | HEILONGJIANG CALIFORNIA INTERN (CN) | 2009-11-11 | — | — | CN | disclosed |
| CN-101239989-A | Nucleotide analog | GILEAD SCIENCES INC (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-100384859-C | Nucleotide analogs | GILEAD SCIENCES INC (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-1244200-A | Nucleotide analogs | GILEAD SCIENCES INC (US) | 2000-02-09 | — | — | CN | disclosed |
| WO-1997030036-A1 | ARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-08-21 | — | — | WO | disclosed |
| CN-85105429-A | The preparation desugar is the method for the carboxylates derivatives of Aaron Copland peaceful (deglucoteicoplanin) too | — | 1987-01-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | PNP, NSUN2, CDA | GAA 1129/4885CYP2D6 506/4885TSHR 1948/4885 |
| US-20110070194-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | PNP, RNGTT, SLC29A1 | GAA 1501/4885CYP2D6 626/4885TSHR 1347/4885 |
| US-20170088561-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | BCL6B, BTD, BCL6 | GAA 76/4885CYP2D6 533/4885TSHR 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.