Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724680 | 1.00 | ADRB2 (0.45) | ADRB2ADRB1ADRB3ATMTSHR | |
| SCHEMBL14724824 | 0.94 | ADRB2 (0.41) | ADRB2ADRB1ADRB3ATMTSHR | |
| SCHEMBL3266108 | 0.91 | ADRB2 (0.39) | ADRB2ADRB1ADRB3ATMTSHR | |
| SCHEMBL16994989 | 0.90 | THRB (0.41) | TSHRCA1CA2THRB | |
| SCHEMBL8723601 | 0.89 | — | — | |
| Ethylene Glycol SCHEMBL14975584 | 0.89 | TSHR (0.50) | ADRB2ADRB1ADRB3ATMTSHR | |
| SCHEMBL8723597 | 0.89 | — | — | |
| SCHEMBL11918809 | 0.87 | CYP3A4 (0.37) | ADRB2ADRB1ADRB3ATMTSHR | |
| SCHEMBL1477016 | 0.85 | — | — | |
| SCHEMBL891970 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285500-B1 | SUBSTITUTED UREAS, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION IN THE FINISHING OF CELLULOSE FIBRES | SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) | 1992-01-02 | — | — | EP | claimed |
| US-4854934-A | CROSSLINKING; CREASE AND SHRINK RESISTANCE | SOCIETE FRANCAISE HOECHST (FR) | 1989-08-08 | — | — | US | claimed |
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-4854934-A | CROSSLINKING; CREASE AND SHRINK RESISTANCE | SOCIETE FRANCAISE HOECHST (FR) | 1989-08-08 | — | — | US | disclosed |