Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301833 | 0.90 | ANPEP (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29283794 | 0.85 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6326119 | 0.85 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6326116 | 0.85 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5197386 | 0.85 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL14279759 | 0.83 | ALDH1A1 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29135214 | 0.83 | HDAC1 (0.34) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL22843973 | 0.82 | GSR (0.39) | ENPEP | |
| SCHEMBL28302938 | 0.82 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1555671 | 0.81 | LTA4H (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160015832-A1 | TRIDENTATE CONNEXON AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2016-01-21 | — | — | US | disclosed |
| US-20160015832-A1 | TRIDENTATE CONNEXON AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2016-01-21 | — | — | US | disclosed |
| US-5854410-A | Oligonucleoside cleavage compounds and therapies | GENTA INCORPORATED (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1995026733-A1 | OLIGONUCLEOSIDE CLEAVAGE COMPOUNDS AND THERAPIES | GENTA INCORPORATED (US) | 1995-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015832-A1 | TRIDENTATE CONNEXON AND USE THEREOF | DNTT, CD2, CD4 | HDAC3 2808/4885HDAC1 3932/4885HDAC2 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.