Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723804 | 0.87 | LMNA (0.68) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL12793245 | 0.86 | POLB (0.88) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL8726184 | 0.84 | POLB (0.73) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7903516 | 0.83 | POLB (0.67) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4050436 | 0.83 | POLB (0.67) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL400508 | 0.83 | POLB (0.67) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL15231957 | 0.83 | POLB (0.67) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7904262 | 0.83 | ALDH1A1 (0.70) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4188547 | 0.82 | POLB (0.65) | POLBALDH1A1LMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2897609 | 0.82 | POLB (0.65) | POLBALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624584-B1 | Piperazine derivatives useful as calmodulin inhibitors | DAIICHI SEIYAKU CO (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5681954-A | HAS CALMODULIN INHIBITORY ACTIVITY; USEFUL IN TREATING DISEASES OF THE CIRCULATORY ORGANS OR IN CEREBRAL REGION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |