Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.55 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258623 | 0.90 | KCNA3 (0.50) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8729254 | 0.84 | HDAC1 (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7364932 | 0.82 | HDAC1 (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7496644 | 0.80 | HDAC1 (0.60) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4310754 | 0.77 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1580334 | 0.76 | LTB4R (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL28658748 | 0.76 | LTB4R (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| Bromide SCHEMBL6049690 | 0.76 | HDAC1 (0.55) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| Bromide SCHEMBL6049689 | 0.76 | HDAC1 (0.55) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8939347 | 0.75 | LTB4R (0.55) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861230-A1 | LIQUID CRYSTALLINE (METH)ACRYLATE COMPOUNDS, COMPOSITION AND METHOD | DENTSPLY INTERNATIONAL, INC. (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997014674-A1 | LIQUID CRYSTALLINE (METH)ACRYLATE COMPOUNDS, COMPOSITION AND METHOD | DENTSPLY INTERNATIONAL INC. (US) | 1997-04-24 | — | — | WO | disclosed |