Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724932 | 0.84 | HDAC1 (0.55) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL6258623 | 0.76 | KCNA3 (0.50) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8939326 | 0.76 | LSS (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL10941544 | 0.75 | LMNA (0.44) | GAAPPARGPPARAALDH1A1 | |
| SCHEMBL8939352 | 0.74 | LSS (0.50) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7364932 | 0.73 | HDAC1 (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL6024662 | 0.73 | ALOX5 (0.53) | PPARGPPARAMAPTPTGESALOX5 | |
| SCHEMBL8939346 | 0.73 | LSS (0.49) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29359699 | 0.73 | LSS (0.54) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8939312 | 0.72 | LTA4H (0.50) | PPARGPPARAMAPTPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861230-A1 | LIQUID CRYSTALLINE (METH)ACRYLATE COMPOUNDS, COMPOSITION AND METHOD | DENTSPLY INTERNATIONAL, INC. (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997014674-A1 | LIQUID CRYSTALLINE (METH)ACRYLATE COMPOUNDS, COMPOSITION AND METHOD | DENTSPLY INTERNATIONAL INC. (US) | 1997-04-24 | — | — | WO | disclosed |