Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019194 | 0.79 | ALOX5 (0.43) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| SCHEMBL524491 | 0.78 | THRB (0.61) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| SCHEMBL523847 | 0.76 | ALOX5 (0.41) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| Bromide SCHEMBL27764709 | 0.76 | THRB (0.59) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| SCHEMBL27621788 | 0.76 | ALOX5 (0.41) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| Bromide SCHEMBL27743790 | 0.74 | ALOX5 (0.40) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| SCHEMBL9628970 | 0.74 | AKR1C1 (0.41) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| SCHEMBL8984710 | 0.73 | ALOX5 (0.44) | ALOX5P2RX4ATMAHRCHRM3 | |
| Bromomethane SCHEMBL208816 | 0.73 | THRB (0.55) | ALOX5P2RX4THRBTDP1CYP2C9 | |
| Bromomethane SCHEMBL208551 | 0.73 | ALOX5 (0.39) | ALOX5P2RX4THRBTDP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770738-A | ANTICHOLINERGIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-06-23 | — | — | US | disclosed |
| US-5654314-A | RESPIRATORY SYSTEM DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 1997-08-05 | — | — | US | disclosed |
| US-4136197-A | HYPOGLYCAEMICALLY AND HYPOLIPIDAEMICALLY EFFECTIVE N-SUBSTITUTED CARBOXYLIC ACID AMIDES | BOEHRINGER MANNHEIM GMBH (DE) | 1979-01-23 | — | — | US | disclosed |