SCHEMBL8725191

SCHEMBL8725191

C#Cc1ccc(C(=NOC)C(C)=NOCc2ccccc2C(=COC)C(=O)OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.40
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7863544 1.00 HIF1A (0.40) HIF1APTGS2
SCHEMBL8725188 1.00 HIF1A (0.40) HIF1APTGS2
SCHEMBL828229 0.90 HIF1A (0.47) HIF1APTGS2
SCHEMBL828228 0.90 HIF1A (0.47) HIF1APTGS2
SCHEMBL7868756 0.89 HIF1A (0.51) HIF1APTGS2
SCHEMBL17949973 0.88 HIF1A (0.42) HIF1A
SCHEMBL7875524 0.88 HIF1A (0.42) HIF1APTGS2
SCHEMBL17949970 0.88 HIF1A (0.47) HIF1APTGS2
SCHEMBL7875521 0.88 HIF1A (0.42) HIF1APTGS2
SCHEMBL7744870 0.85 HIF1A (0.42) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998028262-A1 O-BENZYL OXIME ETHER DERIVATIVES AS PECTICIDES NOVARTIS AG (CH) 1998-07-02 WO disclosed