Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828229 | 1.00 | HIF1A (0.47) | HIF1APTGS2KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL7875521 | 0.92 | HIF1A (0.42) | HIF1APTGS2KDM4ESMN1; SMN2 | |
| SCHEMBL7875524 | 0.92 | HIF1A (0.42) | HIF1APTGS2KDM4ESMN1; SMN2 | |
| SCHEMBL17949973 | 0.92 | HIF1A (0.42) | HIF1ASMN1; SMN2 | |
| SCHEMBL17949970 | 0.92 | HIF1A (0.47) | HIF1APTGS2KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL8725188 | 0.90 | HIF1A (0.40) | HIF1APTGS2 | |
| SCHEMBL8725191 | 0.90 | HIF1A (0.40) | HIF1APTGS2 | |
| SCHEMBL7863544 | 0.90 | HIF1A (0.40) | HIF1APTGS2 | |
| SCHEMBL18291973 | 0.89 | HIF1A (0.42) | HIF1APTGS2 | |
| SCHEMBL8711326 | 0.88 | PTGS2 (0.38) | HIF1APTGS2KDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143275-B2 | Use of triazolopyrimidine derivatives as microbicides | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20110098279-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES | LANXESS DEUTSCHLAND GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-7888371-B2 | For protecting engineered wood, timber, or plastic from phytopathogenic fungi | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | disclosed |
| US-6835842-B2 | Microbiocides; bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | disclosed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | disclosed |
| US-20030207929-A1 | 3-nitroisoxazoles and their use in the protection of materials | LANXESS DEUTSCHLAND GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| US-6638958-B2 | 3-nitroisoxazoles and their use in the protection of materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030166698-A1 | 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS | LANXESS DEUTSCHLAND GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6531496-B1 | Pesticides in crop protection | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-11 | — | — | US | disclosed |
| US-20030040540-A1 | For use as biocides for protecting plants and industrial materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-27 | — | — | US | disclosed |
| US-20020198222-A1 | Use of triazolopyrimidine derivatives as microbicides | LANXESS DEUTSCHLAND GMBH (DE) | 2002-12-26 | — | — | US | disclosed |
| US-20020151570-A1 | Thiosulfonic acid S-esters as agents for protecting material | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-17 | — | — | US | disclosed |
| US-6075019-A | Arylthio-dithiazindioxides and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | HIF1A 2331/4885PTGS2 2032/4885KDM4E 4842/4885 |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | HIF1A 2331/4885PTGS2 2032/4885KDM4E 4842/4885 |
| US-20110098279-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES | ARG2, MSR1, TK2 | HIF1A 1989/4885PTGS2 767/4885KDM4E 3020/4885 |
| US-20020151570-A1 | Thiosulfonic acid S-esters as agents for protecting material | TST, STS, SULT1E1 | HIF1A 2360/4885PTGS2 1152/4885KDM4E 4708/4885 |
| US-20030040540-A1 | For use as biocides for protecting plants and industrial materials | BROX, GPX1, PRDX3 | HIF1A 2185/4885PTGS2 1413/4885KDM4E 4369/4885 |
| US-20030166698-A1 | 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS | GPX1, NOX1, XDH | HIF1A 541/4885PTGS2 459/4885KDM4E 4297/4885 |
| US-20020198222-A1 | Use of triazolopyrimidine derivatives as microbicides | MSR1, FPR1, TK1 | HIF1A 1434/4885PTGS2 931/4885KDM4E 3798/4885 |
| US-20030207929-A1 | 3-nitroisoxazoles and their use in the protection of materials | GPX1, NOX1, XDH | HIF1A 541/4885PTGS2 459/4885KDM4E 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.