Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725188 | 0.89 | HIF1A (0.40) | HIF1APTGS2 | |
| SCHEMBL7863544 | 0.89 | HIF1A (0.40) | HIF1APTGS2 | |
| SCHEMBL8725191 | 0.89 | HIF1A (0.40) | HIF1APTGS2 | |
| SCHEMBL7127227 | 0.86 | HIF1A (0.59) | HIF1APTGS2KDM4EALDH1A1LMNA | |
| SCHEMBL7127228 | 0.86 | HIF1A (0.59) | HIF1APTGS2KDM4EALDH1A1LMNA | |
| SCHEMBL7500390 | 0.84 | HIF1A (0.54) | HIF1AKDM4E | |
| SCHEMBL8444521 | 0.83 | HIF1A (0.60) | HIF1APTGS2KDM4EALDH1A1LMNA | |
| SCHEMBL8444517 | 0.83 | HIF1A (0.60) | HIF1APTGS2KDM4EALDH1A1LMNA | |
| SCHEMBL8543770 | 0.81 | HIF1A (0.51) | HIF1AKDM4E | |
| SCHEMBL7503259 | 0.81 | HIF1A (0.49) | HIF1APTGS2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313344-B1 | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-06 | — | — | US | disclosed |
| EP-0984923-A1 | O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054125-A1 | O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1998-12-03 | — | — | WO | disclosed |