Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.56 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.56 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.56 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.56 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.56 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18482859 | 1.00 | GJB2 (0.56) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8723897 | 1.00 | GJB2 (0.56) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL21657118 | 1.00 | GJB2 (0.56) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL21013113 | 0.89 | GJB2 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL15973204 | 0.86 | HTR1A (0.53) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16632215 | 0.86 | SSTR4 (0.61) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16632214 | 0.86 | SSTR4 (0.61) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL21657199 | 0.85 | HTR1A (0.52) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| Phosphine SCHEMBL7254654 | 0.85 | HTR1A (0.52) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL21657117 | 0.85 | HTR1A (0.52) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832898-A2 | Substituted amino acid derivatives | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |