Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 7/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576156 | 0.81 | ASAH1 (0.49) | ASAH1HPGDKDM4EALDH1A1 | |
| SCHEMBL22252624 | 0.77 | HPGD (0.49) | MIFF2PLGELANECTSG | |
| SCHEMBL29721369 | 0.76 | LMNA (0.48) | MIFF2PLGELANECTSG | |
| SCHEMBL4680991 | 0.73 | HPGD (0.49) | MIFHPGDALDH1A1MGLLFAAH | |
| SCHEMBL1523023 | 0.73 | KDM4E (0.47) | MIFF2PLGELANECTSG | |
| SCHEMBL6757710 | 0.72 | MAPK14 (0.49) | MIFELANEHPGDALDH1A1MGLL | |
| SCHEMBL6764108 | 0.72 | MEN1 (0.48) | MIFF2PLGELANECTSG | |
| SCHEMBL6761320 | 0.72 | HPGD (0.44) | HPGDALDH1A1BRD4 | |
| SCHEMBL6764255 | 0.71 | TP53 (0.45) | HPGDALDH1A1L3MBTL1MGLLFAAH | |
| SCHEMBL6759650 | 0.71 | HPGD (0.47) | MIFHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817826-A | INHIBIT FORMATION OF PROSTAGLANDINS, LEUKOTRIENES; ANTIINFLAMMATION AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0675114-A1 | OXAZOLINONE DERIVATIVE HAVING INTRACELLULAR PHOSPHOLIPASE A 2? INHIBITOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |